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Antidote Powder
Sekiro: Shadows Die Twice

Antidote Powder

Learn how to obtain and use Antidote Powder in Sekiro: Shadows Die Twice. This guide covers its location, effects, and how it helps combat poison.

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Learn how to obtain and use Antidote Powder in Sekiro: Shadows Die Twice. This guide covers its location, effects, and how it helps combat poison.

Antidote Powder is a consumable item in Sekiro: Shadows Die Twice that cures poison status. While not as commonly used as the Healing Gourd, it can be a lifesaver in specific situations where poison is a persistent threat.

  • Antidote Powder — Cures poison status.
Walkthrough
  1. 1
    Antidote Powder can be found as loot in various locations throughout the game.
  2. 2
    It can also be purchased from certain merchants, such as the one found near the Abandoned Dungeon entrance.
  3. 3
    It is sometimes dropped by enemies, particularly those that inflict poison.
Tips
  • While Antidote Powder is effective, learning to manage poison through other means, like specific Prosthetic Tools or by defeating poison-inflicting enemies quickly, is often more efficient.
  • Keep a few on hand for areas or boss fights where poison is a primary mechanic, such as against the Guardian Ape or in the Sunken Valley.

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