Part 19

Explore Part 19 of our Binding of Isaac: Rebirth guide, covering items like Monstros Tooth, Lemon Mishap, and Mom's Bottle of Pills. Learn their effects and strategies.

Alright, let's dive into Part 19 of our Binding of Isaac: Rebirth item guide. We've got some interesting active items here that can really change up how you approach a room, so let's break them down.

First up is an item that feels like a bomb but with a bit more flair. When you use it, a crosshair appears at your feet, and you can move it around with the arrow keys. After a few seconds, a rocket crashes down on that spot, dealing heavy area damage. Just be careful – if you're caught in the blast, you'll take a full heart of damage. Think of it as a portable bomb that you can aim. It's great for boss battles, but you'll want to make sure you've got a clear shot. Missing can be costly, and if you're going to miss, you might as well just use a regular bomb. It's a decent item, but there are other recharge items out there that might offer more bang for your buck.

Next, we have the Lemon Mishap. When you use this, a puddle appears around you, and any enemy that steps in it takes damage. It's a pretty clever item, but it has its downsides. Flying enemies won't be affected, and enemies that can shoot from a distance don't need to get close to your puddle. However, for most ground-based enemies, it can deal some decent damage. If you place it strategically, it can even act as a sort of shield. You'll likely still need to dodge projectiles, which might pull you away from the puddle, so keep that in mind. It's a solid item, especially with its short 2-room recharge time.

Then there's Mom's Bottle of Pills. This one gives you a random pill when used. Now, this item shines when you've got certain other items. If you have Cain's starting Lucky Foot or the PHD, the pills you get are very likely to be stat ups or have positive effects. I've seen players max out stats using Cain with this item, and maxed stats are a huge advantage. Even with the 6-room recharge, if you clear every room on each floor, you can get a good number of pills, leading to a lot of stat boosts. If you don't have those specific items, the Pill Bottle is still useful. Once you've used six pills in a run, their effects will be displayed. You might lose a stat point or two initially, but after that, you can just avoid the bad pills. The benefits usually outweigh the risks. If you get a string of really bad pill effects, you can always ditch the item and look for something else. It's a favorite recharge item for many.

Finally, we have Monstro's Tooth. When you use this, you summon Monstro himself to slam down on an enemy, dealing massive damage. Just a heads-up: if there are no enemies in the room when you use it, Monstro will land on *you* instead, dealing damage. You also can't use this against Monstro himself. It has a 3-room recharge time.