Your friendly guide to Challenge #12: When Life Gives You Lemons in The Binding of Isaac: Rebirth. Learn about the starting items, strategy, and reward.
Alright, let's dive into Challenge #12, "When Life Gives You Lemons." This one's a bit of a curveball right from the start. ## When Life Gives You Lemons This challenge kicks off with you already having Lemon Mishap, 9 Volt, and Habit. You'll also start with one Lemon Party pill. Your main goal here is to defeat Mom. This challenge is available from the get-go, but heads up: there are no Treasure Rooms to be found, which definitely makes things trickier than a standard run. ### Difficulty The biggest hurdle is the absence of Treasure Rooms. This means fewer opportunities to find powerful items that could help you out. ### Strategy * Lemon Mishap is your main attack, but its range is pretty small, so you'll need to get up close and personal with enemies. The Habit and 9 Volt combo is key here. Since you start with 9 Volt, any active item you find will recharge faster. Habit helps even more by charging the active item when you take damage. Keep an eye out for any better activated collectibles to swap in! * If you happen to find the Lost Cork trinket (it's available in Afterbirth † and Repentance), grab it! It significantly increases the range of Lemon Mishap, making it much safer to use. * Shoop da Whoop! is another fantastic find. Because of the 9 Volt, you'll be able to use this powerful active item every single room. ### Reward Completing "When Life Gives You Lemons" (Challenge #12) rewards you with the Card Against Humanity item. ### Trivia * The name of this challenge is a nod to the common saying, "When life gives you lemons, have a lemon party." * One of the fortunes you might get from a Fortune Telling Machine is: "When life gives you lemons, reroll!" Here's a quick look at the challenges in The Binding of Isaac: | Expand [Challenges] | | --- | | Rebirth | | 1. Pitch Black | 2. High Brow | 3. Head Trauma | 4. Darkness Falls | 5. The Tank | | 6. Solar System | 7. Suicide King | 8. Cat Got Your Tongue | 9. Demo Man | 10. Cursed! | | 11. Glass Cannon | 12. When Life Gives You Lemons | 13. Beans! | 14. It's in the Cards | 15. Slow Roll | | 16. Computer Savvy | 17. Waka Waka | 18. The Host | 19. The Family Man | 20. Purist | | Afterbirth | | 21. XXXXXXXL | 22. SPEED! | 23. Blue Bomber | 24. PAY TO PLAY | 25. Have a Heart | | 26. I RULE! | 27. BRAINS! | 28. PRIDE DAY! | 29. Onan's Streak | 30. The Guardian | | Afterbirth † | | 31. Backasswards | 32. Aprils Fool | 33. Pokey Mans | 34. Ultra Hard | 35. Pong | | Repentance | | 36. Scat Man | 37. Bloody Mary | 38. Baptism by Fire | 39. Isaac's Awakening |100% Human-Written. AI Fact-Checked. Community Verified. Learn how AntMag verifies content