Part 13

Famine's primary attack is a scream followed by a horizontal charge that sends him off-screen and immediately reappearing on the opposite side.

His second attack is spawning Pooters. He can spawn them in quick succession but will not spawn more than three on-screen at once.

To counter his charge, stay above or below Famine, as the attack only works horizontally.

There is generally no reason to attack the Pooters as Famine will quickly spawn another. Instead, position yourself out of their range but within range of Famine.

Focus all your projectiles on Famine.

If Pooters enter your range and Famine is at the top or bottom of the room, you can kill the Pooters so they respawn (be brought back to life at a checkpoint after death) near him. Move to the other side of the room to get out of Pooter range while still being able to hit Famine.

You can use Famine's charge attack against Pooters; if he hits them during his charge, they die.

Once Famine takes sufficient damage, his mount and body are destroyed. He can no longer spawn Pooters or charge.

In his second stage, Famine only shoots three drops of blood at a time and moves slowly.

If Pooters are still alive in the second stage, kill them.

Dodge Famine's projectiles and kill him. You can remain stationary and shoot him, moving around just before he shoots to dodge.

Pestilence has two stages. In the first stage, he has his head and rides an undead steed.

His primary attack is throwing area-damaging projectiles that explode on the ground, leaving behind toxic liquid that damages you on contact. This liquid disappears after a while.

His secondary attack is spawning two Chargers, two Spities, or a Charger and a Spity.

Pestilence also leaves a trail of toxic liquid behind him as he moves, which works the same way as the liquid from his projectiles. His movements can be fast and erratic.

In the first stage, keep your distance, ensure you have at least two escape routes, and deal with the spawned Chargers and Spities, which do not respawn rapidly.

Dodge Pestilence's projectiles; if you are far away, they may not hit you, but dodge to the side if you are close enough.

Try to defeat spawned enemies first so you can focus on Pestilence and his attacks. You should defeat them faster than Pestilence can spawn them, allowing you to damage Pestilence simultaneously.

Be mindful of Pestilence's toxic liquid trail cutting off your escape routes. If he moves too close, run far away, even around him if necessary.

After taking enough damage, Pestilence enters his second stage, becoming much easier.

In the second stage, his primary attack is spawning red-bodied flies, which are easily dealt with.

His secondary, less used attack is firing an area-damaging projectile identical to the one in the first stage.

His movements are slower and less erratic in the second stage, and he still leaves a trail of toxic liquid.

In the second stage, stay out of range of his projectiles and deal with the red-bodied flies as soon as they appear.

You should be able to defeat the flies faster than Pestilence can spawn them, giving you time to focus shots on the boss.

War has an upgraded charge attack compared to Famine. He charges horizontally off-screen, reappearing to charge three times in total (bottom, middle, and top areas of the room), before stopping. The order of these charges is random, and the charge is much quicker than Famine's.

To avoid War's charge, stay above or beneath him, as he needs to be directly to your left or right to initiate the attack.

His other attack is a burst of eight blood drops in all directions, which he tends to use with less warning than other bosses. Stay attentive to dodge this.

Once War sustains sufficient damage, he loses his mount and chases you. He is even faster than Lust or a Dormant Mr. Maw after awakening.

Keep running away and shooting projectiles to damage and slow him.

After taking a few shots, War pauses briefly, which is helpful for creating distance.