Part 10

Master Mom, Mom's Heart, and Monstro in The Binding of Isaac: Rebirth Part 10. Learn attack patterns, weaknesses, and strategies for these challenging bosses.

This section covers boss fights against Mom, Mom's Heart, and Monstro in The Binding of Isaac: Rebirth.

Mom

Mom is the boss found in The Depths 2. She is encountered every time.

This battle is frantic, with Mom employing at least two attacks simultaneously.

Mom's Attacks:

• Foot Stomp (Curb Stomp): Watch for shadows on the ground and overhead. Move away quickly when you see them. A grunt often precedes the attack.
• Slap: Occurs when you get too close to an open door. A hand will emerge and damage you. Stay away from doors to avoid this.
• Monster Spawns: When a piece of flesh appears in a doorway, enemies will spawn. These enemies are random and can be anything.

How to Damage Mom:

The general rule is 'If it's flesh, ATTACK IT.'

• The Foot: An immobile target for a short time after a stomp, making it an easy target.
• The Eye: Appears when Mom calls out 'Isaaaaaaaac'. It has no known real use but is an easy way to damage Mom.
• The Hand: Has a fairly short reach; move out of range and attack it.
• The Flesh: Harmless to you, but often blocked by spawned enemies. You might hit it when attacking enemies.

Mom uses 3 of these attacks at random. Stay alert, especially for Mom's foot.

Mom's Heart

Mom's Heart is the boss found in The Womb 2. She is encountered every time.

This battle is simple but can be long. The only way to damage Mom's Heart is by attacking it when it appears.

Strategy:

1. Mom's Heart appears to spawn two random enemies.
2. It stays on-screen and vulnerable for a few seconds before disappearing.
3. Kill the spawned enemies.
4. Mom's Heart reappears and spawns more enemies. This repeats until it's defeated.

General Strategy: Ignore spawned enemies and focus on Mom's Heart until it disappears. The only exception is when two Eyes are spawned; deal with them immediately to avoid heavy damage. Keep moving and focus on one Eye at a time.

Late-Game Strategy: Once Mom's Heart has lost about three-quarters of its health, it stays on screen permanently, spawning enemies as you kill previous ones. It also shoots large blood drops in random directions, which are easy to dodge. If an easy enemy spawns, consider leaving one alive to focus on Mom's Heart while dodging.

This strategy assumes you have good items, stats, and health from progressing through the game.

Monstro

Monstro is a boss found in the Basement.

Monstro's Attacks:

• Small Hop: Monstro hops towards you. Dodge by staying a safe distance away.
• Blood Spray: Monstro sprays blood in your direction with a wide arc. Stay far enough away to avoid it.