Follow this guide to complete Anders' companion quest in Dragon Age: Origins, including finding key items and making crucial decisions.
Alright, let's get Anders' companion quest sorted out! First things first, you'll want to thoroughly loot the area you're in. Check the chest right in front of you, then the wooden crate, the armoire, and another crate on the opposite side. You're looking for some pretty sweet gear: Lorekeeper’s Mittens, Lorekeeper’s Gloves, Blood Promise, Lorekeeper’s Cowl, Lightning Rod, and Aqua Magus. Don't miss any of that!
Next, head north. You'll run into a guy named Rylock. He's going to force your hand – you'll either have to fight him or give up Anders. Make your choice, but be ready for a fight either way. After that, head into the northern room. On the bookshelf, you can find a Potent Health Poultice Recipe and a book called Lyrium: The Voice of the Maker. There are two chests in here; one has an Enchanter Cowl and a Charm of Flame, while the other just has some coin. There's also a shelf tucked away in the back corner that you should loot before you move on.
Once you're done in there, head back to the Chanter. Turn in any quests you've got stacked up. If you're able to, grab the quest “A Donation of Poultices“ from the quest board and turn it in too. Now, make your way to The Crown and Lion inn. Go to the back corner, near where the Innkeeper is standing, and you'll find a Note Fragment. Leave the bar and head towards the door near Constable Aidan. At the end of this catwalk, you'll find another Note Fragment. Grab it, and on your way back, check the chest you pass.
Your next stop is the first house you see when you enter the city. Inside, you'll find Karrem hanging from the ceiling. Loot his body for the Third Note Fragment. After that, return to Alma in the Chantry. Once that's done, you can leave Amaranthine. You can either continue with the main story or go tackle other side quests.
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