Resident Evil 3 (Remake) Nightmare/Inferno Walkthrough

Q: Resident Evil 3 (Remake) Nightmare enemy placement?

Nightmare and Inferno difficulties significantly alter item and enemy placement. Most attacks will put you in critical health unless you have Iron Defense Coins. Inferno reduces healing items further and lacks checkpoints, making it very punishing, especially the early game and final boss. An S-Rank requires 5 or fewer manual saves.

Q: Resident Evil 3 (Remake) Inferno healing items?

Nightmare and Inferno difficulties significantly alter item and enemy placement. Most attacks will put you in critical health unless you have Iron Defense Coins. Inferno reduces healing items further and lacks checkpoints, making it very punishing, especially the early game and final boss. An S-Rank requires 5 or fewer manual saves.

Q: Resident Evil 3 (Remake) S-Rank manual saves?

Nightmare and Inferno difficulties significantly alter item and enemy placement. Most attacks will put you in critical health unless you have Iron Defense Coins. Inferno reduces healing items further and lacks checkpoints, making it very punishing, especially the early game and final boss. An S-Rank requires 5 or fewer manual saves.

Q: Resident Evil 3 (Remake) shop items Nightmare?

Nightmare and Inferno difficulties significantly alter item and enemy placement. Most attacks will put you in critical health unless you have Iron Defense Coins. Inferno reduces healing items further and lacks checkpoints, making it very punishing, especially the early game and final boss. An S-Rank requires 5 or fewer manual saves.

Q: Resident Evil 3 (Remake) Inferno difficulty start?

Nightmare and Inferno difficulties significantly alter item and enemy placement. Most attacks will put you in critical health unless you have Iron Defense Coins. Inferno reduces healing items further and lacks checkpoints, making it very punishing, especially the early game and final boss. An S-Rank requires 5 or fewer manual saves.

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Walkthrough

1
After making any purchases, select New Game and your chosen difficulty.
2
After the opening scenes, make your way to the bathroom and look in the mirror.
3
After Jill wakes up, head to the bathroom again and turn on the light. Make your way back to the living room, turn on the light and answer your phone to have Nemesis break through the wall.
4
Escape the apartment: Run down the corridor. Jill will duck into another apartment and push a heavy shelf down in front of the door. Go to the living room and climb through the open window.
5
Go down the fire escape and climb through another open window. As you make your way through the apartment, Nemesis will crash through the ceiling. After Jill has escaped his clutches, make your way down the burning corridor towards the fire exit for another brief scene.
6
Go down two flights of stairs and approach the ladder. At this point, Nemesis will catch up with Jill again, throwing her through the nearby door. Keep running from Nemesis and when you get through the door at the end, the ceiling will collapse on top of him.
7
Get out of town: Make your way down to the end of the alley to meet Brad Vickers. Follow Brad and when you can, press L3 to start running. When the zombies break through the fence, run over to Brad, keeping to the left to avoid getting chewed. It is possible that you will be grabbed regardless, which results in Jill's death.
8
When you head into Bar Jack, Brad will get bitten by one of the zombies trying to follow you inside. He will tell Jill to get herself to safety while he makes a heroic last stand. Make your way through the alley where Jill will automatically grab the pistol from the dead cop.
9
Afterwards, a zombie will come around the corner. Run away from it and duck under the sign that falls in your path. There will be a zombie standing in front of the gate that you have to get through and another one climbing out of a nearby bus. Wait for the first to lunge towards you and dodge past it. If it's not a perfect dodge you will get chewed and may die. Go through the gate and head through the door at the end into a warehouse. Ignore Dario Rosso as he shuts himself inside the container but pick up the Handgun Ammo (x7) on your way out.
10
Go to the rooftop parking lot: Crawl under the broken fence and cross the road to a parking lot. As you approach the elevator, two zombies, one walking and one crawling, will burst through the door. Turn around and run. Put a long distance between you and shoot the zombie in the body to take it down. If you don't manage to fell it, be prepared to make a perfect dodge. You can avoid the crawling one fairly easily. If you do get bitten, it's not that important so long as you manage to get in the lift - you will be (relatively) safe shortly. Take comfort that you've just got past one of the most difficult sections of the game.
11
Take the elevator up to the roof. Run towards the rescue helicopter only for it to be shot down. At this point, Nemesis will make another appearance. Jill will jump in a nearby car. Press X three times to start the engine. Once the engine is started, hold the R2 button to accelerate and keep holding it.
12
Jill will drive the car into Nemesis and off the roof. During the subsequent scene, Carlos Oliveira will fire a rocket at Nemesis, knocking him down. Afterwards, he will lead Jill to temporary safety in the Redstone Street subway station.
13
Go with Carlos: Start following Carlos through the door that he forces open. For the time being, you are not able to get past Carlos and must wait for him to open a door ahead of you regardless, so don't bother trying to force your way past him. Follow Carlos into the railway carriage for a scene.
14
Get above ground: Afterwards, leave the carriage and head up the steps. Continue up the next flight of stairs. You will find various goodies on some crates, Green Herb (x2), the .44 AE Lightning Hawk and a Hip Pouch.
15
Head through the gate to the Safe Room. Open up the Item Box where you'll find any items you purchased waiting for you. Assuming you bought a Rocket Launcher, you can get rid of your Handgun and Survival Knife and store the herbs for later. If you bought Hip Pouches, you will find them on the crate next to the Item Box.
16
Reactivate power: (Section incomplete in source text)

Tips

On Nightmare and Inferno, pretty much any attack will take you into the red zone unless you are carrying Iron Defense Coins.
For Inferno difficulty, the number of healing items is reduced. If a herb or healing spray mentioned in the text is not present, this is because of the higher difficulty.
Without checkpointing on Inferno, it is much more punishing. The start of the game before you are able to retrieve shop items is very difficult and the final boss is an obnoxious difficulty spike.
An S-Rank requires five manual saves or less, meaning you'll have to pick your save slots very carefully. You only have four saves to play with if you want to hold one for the final boss.
Any death will take you back to your last manual save.
Unless you're an elite gamer who is able to perfectly dodge every attack, you will want the following items from the shop: Infinite Rocket Launcher, Assault Coin (x2), Hip Pouch (x2), Iron Defense Coin (x2), Recovery Coin (x2), S.T.A.R.S. Field Combat Manual.
These shop items require a total of 102400P. You should be able to afford most of these without farming kills, as you must have beaten Hardcore difficulty to access Nightmare, and Nightmare to access Inferno. For reference, 143000P was earned by the time of playing Nightmare difficulty.

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Walkthrough (Nightmare / Inferno)